Bioinformatician for Statistical Genomics of Brain Disorders

Institute of Biological Psychiatry at Mental Health Services, Copenhagen and University of Copenhagen is building an international and highly competitive research environment, and is seeking an extremely talented and highly motivated bioinformatician to work on genomics and systems biology of severe mental disorders. Institutional research profile  The main goal of the institute is to identify causes and mechanisms underlying severe mental disorders. The institute has been a major driver in using array and NGS techniques to identify highly significant and replicated CNVs, point mutations and SNPs. Most recently, the institute has worked to convert these findings into actionable biological insight applying multi-OMICs technologies to biomaterial from the unique, nation-wide Danish biobanks and transgenic animal models, and through genomic-guided clinical studies in humans. This work is part of iPSYCH Initiative for Integrative Psychiatric Research sponsored by the Lundbeck Foundation ( and involves multiple international academic and industrial groups.   Job profile  The right candidate will be primarily responsible for the development of analysis pipelines for sequence data (exome, and RNAseq) and Genome-Wide Association Studies (GWAS). The candidate will collaborate with researchers at the Institute performing data analysis and scientific programming. The candidate will also be responsible for implementation of non-standard statistical analyses of genetic and non-genetic data, under the direction of researchers at the Institute. The goal will be to link genetic disease risk and lifespan trajectories to develop clinical prediction algorithms, capable of stratifying patients into etiological distinct clusters, advancing precision medicine. The fellow will work in close collaboration with colleagues at the Institute while also developing and implementing his or her research ideas and goals. The fellow will work with the institute Lead Scientists and formally report to the Director of the Institute, Professor Thomas Werge.  Qualifications Professional qualifications Holds a MS (or PhD) degree or has equivalent qualifications Extensive experience in genomics, bioinformatics or systems biology Good collaborative, communication and presentation skills Experience in analyzing sequence data and GWAS Experience with statistical analysis packages such as R or MATLAB Programming skills in common languages such as Python, Perl or C++ Personal qualifications: Ambitious and with a strong motivation to obtain established goals Scientifically self-propelling, creative and driven by curiosity  Ability to work independently and structured Open-minded and analytical personality 

We offer  The appointment will be based on the collective agreement with the Confederation of Professional Associations. The allowance will be agreed with the relevant union. The employment will initially be for a period of one year based on a full-time appointment (37 hours per week) with the expectation of extension. The place of work is at the Institute of Biological Psychiatry at the Mental Health Center Sct. Hans located in Roskilde just west of Copenhagen. The institute will be able to provide temporary accommodation at the hospital campus.    Further information  Further information may be obtained from Thomas Werge email: Application  We encourage submission of applications as soon as possible and no later than 1st of May 2019. The application must be submitted as one PDF file and include a cover letter and a professional CV. All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

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